Figured out a way to support cameras with target textures, that avoids errors about depth buffer mismatch.

Assets/Scripts/Fsr2ImageEffect.cs

@@ -80,7 +80,9 @@ namespace FidelityFX
             
             // Set up the original camera to output all of the required FSR2 input resources at the desired resolution
             _renderCamera = GetComponent<Camera>();
+            _originalRenderTarget = _renderCamera.targetTexture;
             _originalDepthTextureMode = _renderCamera.depthTextureMode;
+            _renderCamera.targetTexture = null;     // Clear the camera's target texture so we can fully control how the output gets written
             _renderCamera.depthTextureMode = _originalDepthTextureMode | DepthTextureMode.Depth | DepthTextureMode.MotionVectors;
             
             // Initialize FSR2 context
@@ -134,6 +136,7 @@ namespace FidelityFX
             }
 
             _renderCamera.depthTextureMode = _originalDepthTextureMode;
+            _renderCamera.targetTexture = _originalRenderTarget;
             
             if (_context != null)
             {
@@ -250,7 +253,7 @@ namespace FidelityFX
             _renderCamera.rect = _originalRect;
             _renderCamera.ResetProjectionMatrix();
 
-            if (dest != null && _renderCamera.targetTexture == null)
+            if (dest != null && _originalRenderTarget == null)
             {
                 Debug.LogError("FSR2 is not set to output directly to the backbuffer! Please ensure that FSR2 is the final pass in the image effects chain.");
                 Graphics.Blit(src, dest);
@@ -281,7 +284,7 @@ namespace FidelityFX
             _context.Dispatch(_dispatchDescription, _dispatchCommandBuffer);
 
             // Output the upscaled image to the backbuffer
-            _dispatchCommandBuffer.Blit(Fsr2ShaderIDs.UavUpscaledOutput, _renderCamera.targetTexture != null ? _renderCamera.targetTexture : dest);
+            _dispatchCommandBuffer.Blit(Fsr2ShaderIDs.UavUpscaledOutput, _originalRenderTarget != null ? _originalRenderTarget : dest);
             _dispatchCommandBuffer.ReleaseTemporaryRT(Fsr2ShaderIDs.UavUpscaledOutput);
 
             if (autoGenerateReactiveMask)